Got your thinking cap?

Good. Put it on....
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The opening line of a well-known American novel has had all its vowels removed. Replace them and discover the line.

CLLMSHML

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Okay, as always answer to follow later in the comments. Good luck and happy Friday!

Update: SarahK is both speedy and smart! Whoohoo! And because it's Friday (and I feel like it) I'll give an honorable mention to Ben at the Path Less Traveled. :)